Acid Reflux Drug Linked To More Than Doubled Risk Of Stomach Cancer Study
There are more than 50m prescriptions for proton pump inhibitors in the UK, though they have previously been linked to side-effects and increased risk of death
A drug commonly used to treat acid reflux is linked to a more than doubled risk of developing stomach cancer, researchers have claimed.
Proton pump inhibitors reduce the amount of acid made by the stomach and are used to treat acid reflux and stomach ulcers.
A study published in the journal Gut identified an association between long-term use of the drug and a 2.4 times higher risk of developing stomach cancer. In the UK, there are more than 50m prescriptions for PPIs every year but they have been linked to side-effects and an increased risk of death.
A link between PPIs and a higher stomach cancer risk has previously been identified by academics but never in a study that first eliminates a type of bacteria suspected of fuelling the illnesss development.
Research by the University of Hong Kong and University College London found that after the Helicobacter pylori was removed, the risk of developing the disease still rose in line with the dose and duration of PPI treatment.
They compared the use of PPI against another drug which limits acid production known as H2 blockers in 63,397 adults. The participants selected had been treated with triple therapy, which combines PPI and antibiotics to kill off the H pylori bacteria over a week, between 2003 and 2012.
More Heartburn Drugs Recalled Linked To Cancer
It seems like every time I turn around Big Pharma has come up with a new way to kill us.
Theyve put out drugs that increase stroke risk cause dementia and DOUBLE heart disease risk.
But this latest scandal may take the cake.
The FDA has just sounded the alarm on one of Big Pharmas most popular heartburn drugs because of a MAJOR complication that could not just ruin your life but it could end it.
Heres everything you need to know.
Taking ranitidine? Better read THIS
The heartburn drug in question is called ranitidine, better known as Zantac.
And the reason for the recall?
IT COULD CONTAIN CONTAMINANTS LINKED TO CANCER.
This drug maycontain a nasty chemical known as N-Nitrosodimethylamine .
NDMA is a cancer-causing agent that is used to make stuff like industrial lubricants and rocket fuel.
Yes. Rocket fuel.
The FDA recalled the drug not long ago, but per usual they dragged their feet on the issue and did not recall ALL ranitidine products.
The FDA has finally called for a removal of ALL ranitidine products from the market immediately.
Why? Because the FDA recently discovered that NDMA levels increase the longer ranitidine products are stored especially in hot temperatures.
Not to mention, lab results showed the older the product is, the more DANGEROUS it is.
Folks, if you have Zantac or any generic ranitidine productsitting in your medicine cabinet go toss it in the trash right now.
I recommend trying aloe vera juice to control your stomach acid.
Are Heartburn Drugs Linked To Stomach Cancer
Proton pump inhibitors such as esomeprazole, lansoprazole and omeprazole are extremely popular heartburn medicines. More than 110 million prescriptions for proton pump inhibitors are filled each year. That does not count the tens of millions of pills purchased over the counter. These PPI heartburn drugs were once available only by prescription as Nexium, Prevacid and Prilosec. Now the FDA considers them so safe it cleared them for over-the-counter sale.
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Get More Information About Zantac And Cancer
- If you want to know more about the recent Zantac MDL case, click here:
- If you want to know more about the FDAs views on the subject, read this warning: https://www.fda.gov/news-events/press-announcements/fda-requests-removal-all-ranitidine-products-zantac-market
- Large universities like Harvard have made pronouncements on the subject: Popular heartburn drug ranitidine recalled: What you need to know and do
- Large medical journals have studied this topic in-depth and have put out copious studies with data on the relationship between Zantac, NDMA, and illnesses like cancer: https://www.ajmc.com/view/fda-recalls-all-ranitidine-products-zantac-citing-increased-risk-of-cancer
Potentially Harmful Chemical Detected
In September, the FDA reported that small amounts of NDMA were detected in several brand-name and generic heartburn medications.
This affects the many people who regularly use ranitidine medications to prevent and treat heartburn, ulcers, and gastroesophageal reflux disease .
The FDA started to investigate whether the low levels found in the ranitidine medicines create a health risk.
Although NDMA may cause harm in large amounts, the levels the FDA is finding in ranitidine from preliminary tests barely exceed amounts you might expect to find in common foods, Dr. Janet Woodcock, the director of the FDAs Center for Drug Evaluation and Research, said in a
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What We Know About The Possible Carcinogen Found In Zantac
The popular heartburn drug may produce potentially unsafe levels of NDMA when its active ingredient breaks down
French drugmaker Sanofi recently announced a recall of over-the-counter Zantac, the widely used acid reflux medication, in the U.S. and Canada over concerns of possible contamination from a probable carcinogen. This action followed recalls by manufacturers and retailers of generic versions of the drug, called ranitidine. The recalls have prompted questions about whether the drugs levels of a chemical called N-nitrosodimethylamine which has been linked to cancer in animalspose a more serious health risk than initially reported.
Several blood pressure medications, including the angiotensin receptor II blockers valsartan, losartan and irbesartan, were recalled last year over NDMA contamination. The U.S. Food and Drug Administration first flagged the possible contamination of ranitidine products this September. At that time, the FDA said the NDMA levels found in preliminary tests barely exceed amounts you might expect to find in common foods. But the agency released a statement on Oct. 2 calling the levels unacceptable. Asked to elaborate, FDA spokesperson Jeremy Kahn says, Although the FDA has detected NDMA in limited ranitidine samples at low levels, these levels still exceed what FDA considers acceptable for these products.
Tracing the Risks
A Complex Chemistry
Does Zantac 360 Have This Cancer Risk
Thankfully, Zantac 360 does not carry this potential cancer risk. After discovering NDMA in ranitidine, the FDA requested other H2 blockers be tested for the carcinogen. They found famotidine had no NDMA in it at all. Because it is free of this chemical, there is no current concern of a possible link to cancer.
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Know Your Legal Options
The FDA claims NDMA is only dangerous when ingested in large quantities, yet some patients have been taking Zantac for prolonged periods of time to treat ongoing stomach issues. Because the full extent of the contamination, and the resulting health effects, are yet unclear, its extremely important for consumers who have taken Zantac to be vigilant and proactive. As we all know, cancer is a deadly, aggressive disease, and proactive scans and treatment are the best possible treatment.
If you or someone you love was diagnosed with cancer after taking Zantac, make sure you know your legal options.
Do you have a Zantac injury claim? Contact our attorneys at McCune Wright Arevalo, LLP today to schedule a free consultation.
Does Ranitidine Interact With Other Medications
Since ranitidine is an H2 blocker, it may interact with other medications because H2 blockers can interfere with the bodys ability to absorb certain drugs.
Patients taking ranitidine should tell their doctors about any other medications they are taking before receiving treatment, especially warfarin , ketoconazole, erythromycin, or saquinavir.
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Zantac Lawsuit Attorneys Serving The Us
If you have taken an over-the-counter or prescription form of Zantac and experienced damaging effects to your health as a result, youre not alone and you may be able to sue for compensation.
The award-winning legal team of Florin|Roebig can help. Our seasoned team of personal injury attorneys have extensive experience in expertly handling pharmaceutical lawsuits and possess the skills to build a strong case for a favorable outcome.
We currently have several offices spanning across the U.S. in the states of Florida, Texas, Minnesota, and Colorado.
The top-rated dangerous drug personal injury attorneys of Florin|Roebig include:
- Wil H. Florin, B.C.S.
Because Its Symptoms Are Nonspecific Lung Cancer Is Among The Top Three Cancers Most Often Misdiagnosed
Lung cancer is the biggest killer in both men and women in the U.S. and worldwide. Its prognosis remains extremely poor because doctors tend not to find the disease until it is at an advanced stage. The early symptoms of lung cancer may be a slight cough that does not go away, shortness of breath or respiratory infections that keep coming back, including bronchitis or pneumonia.
Most symptoms of lung cancer are not specific such as fatigue, decreased appetite, and weight loss. It is of the utmost importance to go to the GP and get any unusual changes checked out. If your medical professional fails to thoroughly investigate your symptoms, lung cancer can be misdiagnosed.
When the condition is misdiagnosed or its symptoms are ignored, a patient may not receive appropriate treatment. An inaccurate diagnosis can significantly impact a patient’s outcome and quality of life. It is the responsibility of your doctor to rule out the most serious conditions, including lung cancer. The survival rate for lung cancer is hugely influenced by stage at diagnosis, with five-year survival varying from 92% to 0% for the earliest and latest stages respectively.
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How Do Proton Pump Inhibitors Work
The stomach digests food with the aid of gastric acid, a mix of hydrochloric acid, sodium chloride and potassium chloride. This highly corrosive soup is produced when gastric cells in the stomach secrete the hormone gastrin, which signals parietal cells in the stomach to start pumping acid. PPIs shut down the proton pumps in the parietal cells, cutting off the production of acid. If you are blocking acid production by using a proton pump inhibitor, the body says, I dont have enough acid. Make more. So, the way the body reacts is for G-cells to produce more gastrin, Dr. Perre says. Too much gastrin may stimulate the growth of gastrointestinal tumors. Ironically, proton pump inhibitors often are prescribed to treat acid reflux, also called gastroesophageal reflex disease , or H. pylori infections, conditions that may increase the risk of stomach and esophageal cancers. It is a double-edged sword, he says.
Symptoms And Diagnosis Of Possible Zantac Cancer
Like most serious medical issues, knowledge and prevention are key. You need to be diagnosed with cancer to fight it effectively. Specifically, you need to know what kind of cancer you have and how you got it .
Many brand-name ranitidine medications or other medications you or a loved one take may be a human carcinogen. According to the FDA and general medical community, medical advice diagnosis or treatment can make a vital difference.
Cancer is a broad term referring to a condition where cells in the human body become diseased and then spread. It can develop in many ways, and it can take on many different types of symptoms.
Fortunately, some symptoms of cancers are common and can be used to spot the disease early on in its progression.
Here are some early warning signs if you are trying to spot Zantac cancer:
If you suspect that you may have cancer, your physician may order advanced diagnostic screening procedures. It frequently begins with a simple body survey followed by a physical examination where the physicians can feel the affected body parts for possible lumps or bruises.
If that does not suffice, imaging tests can give the doctor a more granular level view of what is happening at the cellular level. Finally, they can have you undergo a biopsy, where they will lance or cut out a part of the suspected malignant mass and test it.
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Try This Heartburn Medication Instead
The good news is H2 blockers, another class of heartburn medications such as Pepcid and Tagamet , are safer alternative medications to the PPIs. The same study using H2 blocks as control medications to the PPIs showed that the stomach cancer risk of PPIs is 2-8 times higher than the H2 blockers.
Interestingly, the Presidents health summary published by The White House on November 19, 2021, revealed that the H2 blocker drug Pepcid was chosen by The White House physician to treat Presidents heartburn symptoms and acid reflux disease. This decision may be because this drug has not yet been linked with reported cancer risk.
Every medication has indications and side effects, including the H2 blockers Pepcid and Tagamet. You should consult with your doctors to choose the appropriate medication to treat your heartburn and acid reflex based on your conditions.
Prevention is better than treatment. To avoid heartburn, you should:
- eat smaller and frequent meals
- avoid late-night eating and
- not exercise right after meals
We hope these heartburn-smart approaches could prevent or reduce your heartburns during this holiday season.
Study Links Popular Heartburn Drugs To Esophageal Cancer
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Drugwatch has a stringent fact-checking process. It starts with our strict sourcing guidelines.
We only gather information from credible sources. This includes peer-reviewed medical journals, reputable media outlets, government reports, court records and interviews with qualified experts.
Popular heartburn drugs prescribed to prevent esophageal cancer may actually cause the disease, according to a new study in Cancer Epidemiology. The drugs include familiar names such as Prilosec, Nexium and Prevacid. They are part of a class of drugs called proton pump inhibitors.
The American Gastroenterological Association recommends prescribing PPIs for all Barretts esophagus patients. Long-term reflux causes the condition. People with Barretts esophagus face a higher risk of developing esophageal cancer.
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What Type Of Cancers Are Associated With Zantac And Zantac Generic Drugs
Zantac is a medication that belongs to a class of drugs known as H2 blockers. These medications are used to treat heartburn, acid reflux, and GERD .
The problem with this type of drug is that it can cause cancer. The CDC has identified NDMA as a probable human carcinogen causing cancer when inhaled or ingested in large amounts over long periods. This chemical was found within Zantac products sold in the United States between 1983 and 2019.
At Rosenfeld Injury Lawyers, LLC, our personal injury lawyers are legal advocates from injured victims harmed by defective products, medical devices, and medications. Our law office helps individuals learn if they qualify to join others in suing Zantac drugmakers for injuries caused by exposure to NDMA through these medications.
A qualified attorney can help by reviewing your case and determining whether or not there was adequate warning provided before you started taking these medications daily without first discussing them with your doctor. Call our dangerous drug attorneys at 424-5757 or use our online contact form.
Zantac use has been associated with various cancers including: Bladder, Breast, Colorectal, Esophageal, Gastric, Intestinal, Kidney, Liver, Lung, Pancreatic, Prostate
Until the manufacturers recalled the product, many people took Zantac for stomach and intestinal issues, including ulcers, acid reflux, stomach acid, or peptic ulcer disease.
Zantac Products Have Dangerous Levels Of Ndma
The initial tests found NDMA in Zantac products claimed that the level was not dangerous. However, drug companies and stores like CVS pulled the Zantac products from the shelves out of an abundance of caution and to protect themselves from what appears like it could be a massive legal liability.
Unfortunately, subsequent testing of Zantac and other medications began to reveal a more dangerous truth. The levels of NDMA in these tests were high enough to potentially cause cancer. In some cases, these levels were multiples of the acceptable daily limit.
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Food And Drug Administration Concerned People Might Get Cancer After Taking Zantac
Many people take the brand name Zantac and other kinds of antacids to treat heartburn, acid reflux, and other problems. However, the government has given us reason to think it might cause cancer. Zantac and other ranitidine products contain N Nitrosodimethylamine NDMA high levels of NDMA may lead to certain types of cancer.
If you have been diagnosed with cancer, contact us to discuss your legal options. Our law firm can help you or your loved one investigate if Zantac causes cancer.
We have worked with many families dealing with this terrible issue, including liver cancer, peptic ulcer disease, ranitidine exposure, bladder cancer, and other problems.
Drug manufacturers that make a product that contains NDMA, including the brand name Zantac, should be held responsible. Talk to an attorney if you have taken Zantac and wonder whether there were unacceptable levels, or even low levels, of nanograms per NDMA.
Rosenfeld Injury Lawyers LLC reviews prescriptions and medical advice diagnoses to see if they have possible human carcinogens or other cancer-causing materials in the United States. For example, a brand name Zantac or other N Nitrosodimethylamine used to treat you or your loved one should not increase cancer risk.
If they did, you might be able to get a recovery. Contact our law firm to see what your legal options may be after your cancer diagnosis. We help people with Zantac cancer lawsuits.
Showing The Link Between Your Zantac Use And Cancer Diagnosis
Demonstrating how your Zantac use led to or contributed to the development of cancer is crucial to establishing a strong claim. For example, if you only took prescription Zantac for a few weeks prior to your diagnosis, you may not be able to prove this element of your claim.
However, if Zantac was part of a long-term regimen for treating heartburn or a related condition, and you later developed cancer while still taking the medication, you may be eligible to file a Zantac lawsuit.
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