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Heartburn Medication That Causes Cancer

Zantac Carcinogen: What Is Ndma

CVS stops selling Zantac, other heartburn medication over cancer fears

NDMA can also be formed during the cooking of foods, especially food such as cured meats and fish because they contain sodium nitrite as a preservative. It is also found in:

  • Vegetables
  • Beer
  • Tobacco smoke

Preliminary testing by the FDA shows some samples of Zantac and ranitidine contain higher levels of NDMA than food.

Although human studies are limited, NDMA is listed as a probable carcinogen to both animals and humans. It is still unknown how ranitidine was contaminated with NDMA, as found in laboratory tests.

There is a possibility that ranitidine is unstable and breaks down on its own to form NDMA. The FDA-approved acceptable amount of NDMA intake is 96 nanograms per day. Studies have shown that when ranitidine mixes with the gastric fluid and sodium nitrites that stimulate the digestion process, high amounts of NDMA are produced. Exposure to simulated stomach conditions caused ranitidine to produce approximately 304,500 ng of NDMA per tablet.

It is also possible that generic versions of Zantac are contaminated with NDMA when manufactured in other countries without strict quality control standards.

The Food and Drug Administration reports that its independent testing has shown that the heartburn medications Pepcid, Tagamet, Nexium, Prevacid, and Prilosec do not contain the chemical NDMA.

What Should I Do Next

Research on the dangers of NDMA in Zantac is still ongoing. It is not certain if previous lots of Zantac contained dangerous doses of the toxin, or how much. Therefore, being proactive about your health and thoroughly documenting your use of Zantac or generic ranitidine is crucial. The same is true for any loved ones you know who take Zantac.

If you or a loved one has been diagnosed with cancer or suffered other serious side effects of Zantac, dont hesitate to contact Dreyer Boyajian LLP by calling today. Our attorneys in Albany and Saratoga Springs have extensive experience with defective product cases, including those involving dangerous drugs. Your initial consultation is free, and you dont owe us a cent until we prevail in your case.

Did Heartburn Medication Cause Your Cancer

You may be part of a mass tort case if you have taken any of the heartburn drugs mentioned above, then developed cancer. You owe it to yourself and your family members to explore any avenues for compensation, including filing a lawsuit.

At the Dailey Law Firm, P.C., our team of skilled lawyers and professionals provide sound and current legal representation that you need. Call us at 844-342-5353 to set up a free consultation or use the Contact Form on our website. Theres no fee for personal injury cases unless we win.

We represent clients throughout the entire United States. You can reach us online or visit one of our offices in Detroit, Michigan Chicago, Illinois or Valparaiso, Indiana.

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Who Can File A Zantac Lawsuit

OnderLaw, LLCAntacid Lawsuit The choice of a attorney is an important decision and should not be based solely upon advertisements. Disclaimer: The accident, injury, personal injury, and/or other legal information offered herein by OnderLaw, LLC, is not formal legal advice, nor is it the formation of an attorney client relationship. In order for our firm to be considered your attorney there must be a signed agreement between the client and the firm. Any results set forth herein are based solely upon the circumstances of that particular case and offer no promise or guarantee on the outcome of any other case.

OnderLaw, LLC is a National Law Firm based in St. Louis, Missouri representing clients throughout the United States in national federal MDL products liability litigation.

Ndma Levels Creep Up After Manufacture

New research uncovers link between heartburn tablets and ...

Ranitidine was a commonly used heartburn and ulcer prescription and over-the-counter medication for decades before it was recalled by the FDA on April 1, 2020. It may now be the canary in the coal mine for the post-manufacturing creation of NDMA.

In one study, investigators found that ranitidine contained only 18 nanograms of NDMA after it was manufactured. However, when stored at 158 degrees Fahrenheit for 12 days as if the drug had been left in a hot car NDMA dosages rose above 140 ng. This is only slightly above the 96 ng limit the FDA has deemed safe, but this was after just 12 days.

In another study, storing ranitidine where it was exposed to higher temperatures or high humidity enhanced the creation of NDMA over time. This suggests that some medications can leave the factory with a safe amount of NDMA but if kept for too long at home or on the store shelf can exceed known acceptable limits by the time patients use them.

In a January 2021 study in JAMA Network Open, investigators simulated the stomach environment and found that when ranitidine was exposed to an acidic environment with a nitrite source, these chemicals could create more than 10,000 ng of NDMA. However, FDA researchers more recently found that the earlier experiment used nitrite levels far beyond what would ever be found in the body. When they reran the study with normal dietary levels of nitrite, only a minimal amount of NDMA was created.

Read Also: What Do You Eat When You Have Heartburn

What Types Of Cancer Does Zantac Cause

Zantac and other ranitidine products contaminated with NDMA, a probable human carcinogen, may be linked to many types of cancer, including bladder cancer, colon cancer and prostate cancer. Its important to know that the research on this topic is still new and scientists havent found solid evidence that says Zantac causes any type of cancer. But they cannot rule out the drugs cancer causing potential either.

According to lawyers accepting Zantac cancer cases, many people who developed cancer after taking ranitidine didnt have a family history of cancer or genetic markers for the disease. Their treating physicians stressed that the cancer was caused by something environmental. NDMA is an environmental contaminant.

Types of cancer caused by Zantac include:

  • Breast cancer

Other potential cancers include stomach, colorectal, esophageal, bladder, breast, liver, prostate, pancreatic, ovarian and melanoma.

In at least two studies, one in 2004 by the National Cancer Institute and another in 2016 by Teng Zeng and William A. Mitch of Stanford University, researchers found potential links between ranitidine and bladder cancer, according to Valisure. But they didnt find proof of causation.

A survey of 24,000 patients at Memorial Sloan Kettering Cancer Center found that ranitidine use was associated with an increased chance of presenting with breast, testicular, thyroid and kidney cancer, according to Adamson and Chabner.

Heartburn Drug & Cancer: Does The Link Hold

June 21, 2021 — In 2016, researchers had some very bad news for anyone taking antacids. They found that healthy men and women who took a normal dose of the heartburn medicine ranitidine, often known by the brand name Zantac, had extremely high levels of a chemical known as NDMA, a probable cancer-causing substance.

NDMA levels in their urine increased by 400-fold after taking a dose of the antacid, the researchers found. Their research and that of others set off a cascade of events that eventually led to the FDA requesting the recall of Zantac and its many generic versions in April 2020.

Now, however, the co-authors of that paper have asked the journal, Carcinogenesis, to retract that paper, and the journal has. In the retraction notice, the journal editors said that ”the authors have informed the journal that their NDMA measurements are not reliable.” The problem has to do with the method they used to measure the NDMA levels. They found levels of NDMA as high as 47,600 nanograms — much higher than the 96 ng the FDA says is an acceptable daily level of NDMA from a drug.

Could this new wrinkle mean a return of ranitidine, a best-selling drug since the FDA approved it as Zantac in 1983? Sales of Zantac topped $136 million in 2019, according to Statista. The drug works by reducing acid production in the stomach. Besides heartburn, it was used to treat ulcers and throat and stomach problems.

Read Also: What Gives You Heartburn At Night

Why Has Zantac Been Recalled

In a broad sense, the ultimate purpose of any product recall is to help improve consumer safety by removing the products from shelves. In this case, the recall serves to reduce the risk of exposure to cancer-causing substances found in Zantac and ranitidine. For this reason, you should immediately cease any Zantac consumption, and report any retailers who are still selling or distributing Zantac or any other dangerous drugs.

Join A Free Prilosec Nexium Lawsuit Investigation

FDA: Probable carcinogen in OTC heartburn drug

If you qualify, an attorney will contact you to discuss the details of your potential case at no charge to you.

PLEASE NOTE: If you want to participate in this investigation, it is imperative that you reply to the law firm if they call or email you. Failing to do so may result in you not getting signed up as a client or getting you dropped as a client.

E-mail any problems with this form to:

Does Nexium Cause Stomach Cancer? Due to the popularity of heartburn medications, many people are now asking questions about whether or not there are serious side effects with… Read More

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Does Nexium Cause Stomach Cancer

Due to the popularity of heartburn medications, many people are now asking questions about whether or not there are serious side effects with these drugs. One question has to do with whether or not Nexium could cause stomach cancer. More research has pointed to a possible connection, especially when a user is taking Nexium for the long term.

Other Drugs Need Closer Investigation

The bodys ability to create NDMA after taking ranitidine seems limited. But the fact that NDMA can be generated as ranitidine sits on the shelf or medicine cabinet is still concerning, and this same phenomenon might occur in other drugs as well.

In another study, investigators added chloramine, a disinfectant routinely added to sterilize drinking water, to water samples that contained one of several medications that are structurally similar to ranitidine. They found that several commonly used drugs, including antihistamines , a migraine drug , another heartburn drug and a blood pressure drug all generated NDMA.

It is unclear whether the amount of NDMA created by these drugs when stored in hot and humid environments is dangerous, as with ranitidine. I believe that more studies need to be done right away to find out. It is always better to be safe than sorry, particularly when dealing with a possible carcinogen.

Editors note: This is an updated version of an article originally published on February 4, 2021.

Read Also: What Foods Can Relieve Heartburn

What Is Ndma And What Harm Can It Cause

NDMA is an environmental contaminant that is found in water and foods, including dairy products, vegetables, and grilled meats. Its classification as a probable carcinogen is based on studies in animals studies in humans are very limited.

It is important to know that the NDMA in ranitidine products does not pose any immediate health risks. Neither the FDA nor Novartis/Sandoz or Apotex have received any reports of adverse events related to NDMA found in ranitidine. Although classified as a probable carcinogen, NDMA may cause cancer only after exposure to high doses over a long period of time. NDMA is one of the same impurities that was found in certain heart medications beginning last year and that resulted in the recall of many products.

Heartburn Medicine Cancer Faqs

Heartburn Drugs and Cancer Risk: What You Need to Know ...

Our attorneys handling acid reflux medicine cancer cases have compiled answers to common questions. For more detailed information on a particular drug, follow the links below.

What kind of heartburn medicine causes cancer?

Available both over-the-counter and by prescription, heartburn and acid reflux medicines that have been found to cause cancer fall in two drug categories: PPIs and H2 blockers. Both serve to reduce the amount of stomach acid produced by the body in order to treat heartburn, acid reflux, and other esophageal complaints.

Which heartburn medicine has been recalled for cancer?

Zantac and many forms of generic Zantac, or ranitidine, have been recalled. The list currently includes:

  • Sanofi Zantac recall
  • Dr. ReddyĆ¢s Laboratory generic Zantac ranitidine recall
  • Walmart Equate Generic Zantac ranitidine recall
  • Walgreens Wal-Zan generic Zantac ranitidine recall
  • CVS generic Zantac ranitidine hydrochloride recall
  • Target Up & Up generic Zantac ranitidine recall
  • Kroger generic Zantac ranitidine recall
  • RiteAid generic Zantac ranitidine recall by Apotex
  • Perrigo Company generic Zantac ranitidine recall
  • Cool Mint generic Zantac ranitidine recall by RiteAid
  • Lannett Company generic Zantac ranitidine syrup recall
  • Sandoz / Novartis generic Zantac ranitidine hydrochloride capsule recall

What kind of cancer does acid reflux medicine cause?

Who can file a lawsuit for heartburn drug cancer?

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Is The Fda Going To Recall Nexium Prilosec Or Prevacid

Under federal law, drug manufacturers bear responsibility for the content of their warning labels, not the FDA. The FDA does has enforcement mechanisms, and the FDA sometimes forces drug manufacturers to add certain warnings, but the FDA doesnt have nearly enough resources to monitor every side effect for every drug. Federal law requires drug companies do that, and requires those same companies to add warnings whenever there is reasonable evidence of a causal association. Our lawyers believe there is reasonable evidence of a causal association and that the companies behind these antacids should have added a warning.

Gastric cancer isnt the only serious risk of drugs like Nexium and Prilosec. Some studies have tied the use of antacids in pregnancy to a higher rate of asthma in children, and others have found PPI users have a greater chance of developing dementia and an increased risk of death from all causes, particularly with long-term use and in patients who dont have gastrointestinal conditions.

The medical community has started to recognize how proton-pump inhibitors are over-prescribed. As several researchers noted in a recent article,

The medical community is starting to recognize that proton-pump inhibitors are overused and are particularly dangerous when used long-term. But for many people this advice is coming too late, and the drug companies must be held accountable for the damage they caused.

Popular Heartburn Medicine Being Linked To Cases Of Specific Cancers In Growing Number Of Lawsuits

Zantac and generic Ranitidine have been recalled, forcing patients to seek other solutions, and question cancer diagnoses.

CLEVELAND, Ohio – Roughly one in five Americans, suffer from the pain and discomfort of heartburn.

But a popular medication, Zantac, thats been around for decades and has offered relief, has been voluntarily recalled over concerns about the level of NDMA, a probable human carcinogen.

So, what are patients to do now? And is it too late for those whove been on these medications long term?

Are you among the roughly 1 in 5 Americans who suffers from heartburn?Many self-medicate with OTC options.Others have…

Posted by Jen Picciano on Tuesday, March 3, 2020

Millions of Americans who suffer from heartburn use whatever they can to ease their discomfort.

I was continuously on Zantac. I had it in my duty bag, trunk of my zone car, locker at work, said Michael Konn.

For nearly 19 years, Konn used Zantac to treat his acid reflux.

He was an otherwise healthy guy, who worked as a patrolman with the Cleveland Police Department for 15 years, when he was diagnosed with bladder cancer.

I went to the bathroom and started urinating blood. I was scared, he said.

His doctor asked him about common risk factors like a family history of bladder cancer, smoking or factory work.

But none applied to then 37 year old Konn.

He was surprised, he said youre very young. You usually get this in you 70s, he recalled his doctor saying.

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Us Pharmaceuticals Not Required To Label Drug Sourcing

To make matters worse, the large majority of APIs are made in factories in China and India. U.S. pharmaceutical companies are not obligated to let American consumers know their drugs are being sourced from foreign countries.

The FDA does a poor job of checking these drugs. In fact, less than 1% of drugs are tested for impurities before they come into the U.S. Inspection of overseas factories by the FDA is in sharp decline. Despite opening three offices in China over a decade ago and vowing increased monitoring, only the Beijing office is still open.

Meanwhile, the FDA says it, along with other world regulators, is considering requiring new testing during the manufacturing process to reduce contamination of drugs. According to Reuters, spokesperson Janet Woodcock, the director of the FDAs Center for Drug Evaluation and Research, said that the FDA is simply going to have to be more vigilant: I think youll see tests added at the appropriate point during the manufacturing.

Jacqueline is a rocket scientist turned writer. She covers health, science and tech news for Citizen Truth. In her first career, she managed experiments & data on the Space Station & Shuttle.

Should I File A Heartburn Medication Zantac Cancer Lawsuit

Major pharmacies pulling popular medication for cancer-causing agents

If you or a loved one was diagnosed with stomach cancer, breast cancer or bladder cancer after taking heartburn medication such as Zantac or another ranitidine medication, you may qualify to file to join a Zantac cancer lawsuit settlement.

Learn more by filling out out the form on this page for a free case evaluation by a heartburn medication cancer injury lawyer.

After you fill out the form, the attorneys who work with Top Class Actions will contact you if you qualify to let you know if an individual lawsuit or class action lawsuit is best for you.

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