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Is Nexium Good For Heartburn

Healing Of Erosive Gerd

Nexium Control® For heartburn protection around the clock

Several clinical trials have compared esomeprazole with other PPIs in healing of erosive GERD . Studies reported in Table 2 had a similar double-blind, randomized design they included intention-to-treat analyses of healing rates, and, as a secondary endpoint, evaluation of therapy effect on GERD symptoms. Also, all studies included patients who had endoscopy-confirmed erosive GERD at baseline. Follow-up endoscopy was performed at 4 weeks and at 8 weeks, except for one study in which patients underwent first follow-up endoscopy at 4 or 6 weeks and second follow-up endoscopy at 8 or 10 weeks . Although at least two randomized studies comparing esomeprazole with each of the other PPIs were identified, no comparative studies of esomeprazole vs rabeprazole in erosive GERD could be found.

Reasons To Recommend Nexium Control

  • 24 hour relief and protection from frequent heartburn
  • NICE guidelines recommend PPIs as first line prescription treatment for frequent heartburn
  • Treats the cause and symptoms of frequent heartburn by reducing the production of stomach acid. Just one tablet a day provides 24hr protection
  • As the #1 acid blocker brand worldwide, it has been used by millions of patients
  • A short term treatment which gives the oesophagus some time to heal

Avoid Tight Fitting Clothes

Things cinched tightly about your waist or middle can worsen heartburn. If you have super tight jeans on, when you sit down, the waistband is going to sink into your abdomen region. Same goes for tight belts-and even shirts can be a problem for some. This is because all of the above puts extra pressure on your lower esophageal sphincter, which make it more likely stomach contents, will push through and youll experience reflux.

Recommended Reading: What Can Help With Heartburn And Indigestion

Drug Interactions Of Protonix Vs Nexium

Protonix and Nexium, like other PPIs, interact with many of the same medications. These PPIs should be monitored or avoided with other drugs that are dependent on stomach acidity for absorption. Drugs that are dependent on stomach acidity for absorption include iron salts, erlotinib, ketoconazole, and mycophenolate mofetil.

Protonix and Nexium can also interact with antiretroviral drugs, or drugs that are often used to treat HIV. PPIs can increase or decrease blood levels of antiretroviral drugs, which can lead to an increased risk of toxicity or decreased effectiveness with antiretroviral drugs.

The use of Protonix or Nexium with warfarin may increase the risk of bleeding.

Nexium should be monitored or avoided with diazepam since it can increase blood levels of diazepam and lead to an increased risk of adverse effects. The use of Nexium and clopidogrel together should also be avoided. Nexium can decrease how well clopidogrel works in the body, which can increase the risk of blood clots.

Drug

Consult a healthcare professional for other possible drug interactions

Important Safety Informationnexium Capsules And Delayed

Nexium Delayed Release 24 Hour Heartburn Relief Capsules, 20 Mg, 28 ...
  • Symptom relief does not rule out the presence of other serious conditions. Talk with your doctor
  • Talk to your doctor about serious side effects, including:
  • Kidney problems may happen at any time during treatment with NEXIUM. Call your doctor if you have a decrease in the amount that you urinate or if you have blood in your urine
  • NEXIUM may increase your risk of getting severe diarrhea. Call your doctor right away if you have watery stool, stomach pain or fever that does not go away
  • NEXIUM may increase the risk of bone fractures of the hip, wrist, or spine if you take multiple daily doses for a year or longer
  • Some people who take proton pump inhibitors , including NEXIUM, develop certain types of lupus erythematosus or have worsening of the lupus they already have. Call your doctor right away if you have joint pain or rash on your cheeks or arms that gets worse in the sun
  • Low vitamin B12 if you have been on NEXIUM for a long time
  • Low magnesium levels if you take NEXIUM
  • Stomach growths , especially if you take PPIs for more than 1 year
  • Tell your doctor if you have low magnesium levels in your blood, have liver problems, or if you are or planning to be pregnant or breastfeed
  • Do not take NEXIUM if you are taking a medicine that contains rilpivirine used to treat HIV-1
  • Do not take NEXIUM if you are allergic to esomeprazole magnesium or any of the ingredients in NEXIUM, or are allergic to any other PPI
  • Approved Uses for NEXIUM

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    What To Do If Ppis Arent Stopping Your Reflux Symptoms

    When your acid reflux symptoms are not being controlled by medication, its time to see a gastroenterologist to discuss your options, specialists say.

    In some patients, gastroesophageal reflux disease symptoms are so powerful they overwhelm proton pump inhibitors such as Prilosec, Prevacid and Nexium, leaving heartburn, regurgitation and other symptoms unchecked.

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    The PPI gets rid of heartburn in about 80 percent of the people who are taking one dose a day, says Joel Rubenstein, M.D., M.Sc., director of the Barretts Esophagus Program and an associate professor in the Division of Gastroenterology at the University of Michigan.

    Reflux or regurgitation, with the effortless movement of stomach contents into the esophagus, is more difficult to get rid of, so thats about 60 to 70 percent of people having their symptoms resolved.

    So what can be done for the other patients?

    Visit a gastroenterologist, says Rubenstein, who is also a research scientist at the Veterans Affairs Center of Excellence for Clinical Management Research.

    One potential problem is that patients may have self-diagnosed without ever seeing a gastroenterologist and purchased a PPI over the counter. Self-diagnosis also can lead to misunderstanding or not following the medicines directions, impacting its effectiveness.

    What Can I Take Instead Of Nexium

    Other drugs in the same category of Nexium include Prilosec, Protonix, Prevacid, and Aciphex. Consult your healthcare provider for a recommendation if Nexium is not working for you.

    In addition to taking a PPI or another medication for your symptoms, you can make dietary changes. Some foods that can help reduce acid are bananas, melon, whole grains, yogurt, lean proteins, and green vegetables .

    Also, try to avoid foods that are fried, high in fat, or spicy. Other irritating foods and drinks to avoid include pineapples, citrus fruit/juices, tomatoes/tomato products, garlic, onions, alcohol, carbonated beverages, coffee, tea, chocolate, and mint. Keeping a food diary may help you to narrow down which foods and beverages help or hurt your symptoms.

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    Treating Heartburn And Gerd

    Heartburn is a feeling of burning pain in your lower chest, behind the breastbone. It comes from acid backing up from your stomach to your throat. You may have seen ads for heartburn drugs, such as Nexium, Prilosec or Prevacid. These drugs are called PPIs . They keep the stomach from making too much acid. They have been shown to heal irritation of the tube between the throat and the stomach .

    In most cases, you dont need a PPI for heartburn. You can get relief from a less powerful drug. And when you do need a PPI, you should take the lowest dose for as short a time as possible. Heres why:

    Ppis Can Change The Way Other Drugs Work

    Nexium Control® For heartburn protection around the clock

    PPIs interact with some common prescription drugs. For example, some PPIs can reduce the blood-thinning effect of the drug Plavix , according to the US Food and Drug Administration. This can increase the risk of heart attack and even death. If you take Plavix, talk to your doctor about whether you should take a PPI.

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    The Effects Of Esomeprazole On Esophageal Acidity

    Two studies have assessed the effect of esomeprazole on intraesophageal pH profiles compared to other PPIs. In a double-blind, randomized, cross-over study in 35 patients with GERD symptoms, esomeprazole 40 mg od was compared with pantoprazole 40 mg od as to their effects on intraesophageal pH . At baseline the median percentage of total time with pH < 4.0 was 20.1% in the esomeprazole and 21.3% in the pantoprazole group. After 7 days of repeated administration, this time was reduced to 0.9% and 2.6% respectively, and the mean within-subject differences in mean 24-hour pH values between pre- and post-treatment values were 19.2% and 18.7% respectively. The Hodges-Lehmann estimate for the mean within-subjects differences in mean 24-hour pH between pre- and post-treatment values for the two PPIs was 2.86% and the corresponding 90% CI was within the equivalence range set at ┬▒ 10% . In another open-label randomized study, esomeprazole 40 mg od was compared with lansoprazole 30 mg od in 30 patients with complicated GERD . Normalization of total and supine nocturnal esophageal acid exposure was achieved in 75% vs 28% and 93% vs 50% of patients in the esomeprazole and the lansoprazole group, respectively .

    Esomeprazole May Cause Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:

    • headache
    • severe diarrhea with watery stools, stomach pain, or fever that does not go away
    • rash on cheeks or arms that is sensitive to sunlight
    • increased or decreased urination, blood in urine, fatigue, nausea, loss of appetite, fever, rash, or joint pain

    People who take proton pump inhibitors such as esomeprazole may be more likely to fracture their wrists, hips, or spine than people who do not take one of these medications. People who take proton pump inhibitors may also develop fundic gland polyps . These risks are highest in people who take high doses of one of these medications or take them for one year or longer. Talk to your doctor about the risk of taking esomeprazole.

    Esomeprazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

    If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .

    Also Check: Do Bananas Give You Heartburn

    Precautions Before Taking Nexium

    Nexium may not be safe or effective for everyone. Make sure you discuss the risks and benefits of the medicine with your medical provider before taking it.

    If you need to, schedule an appointment with your medical provider. This will allow you to ask questions about Nexium and other PPIs as well as give your medical provider a complete list of your medications and discuss your medical history.

    Before taking Nexium, tell your medical provider:

    • About any medications you are allergic to, especially if you are allergic to any ingredient in esomeprazole or other PPIs.
    • If you are taking blood thinners, HIV medications, supplements, methotrexate, antifungal drugs or other medications that may react with Nexium. You may have to adjust your levels of medication.
    • If you are taking vitamins or supplements, including St. Johns Wort. You may have to stop taking some of them while taking Nexium.
    • If you are pregnant or plan to become pregnant.
    • If you have autoimmune disease, liver disease, low vitamin B-12 levels, low magnesium or osteoporosis.

    If you have taken over-the-counter Nexium for longer and you continue to suffer serious heartburn or chest pain, wheezing, abdominal pain, bloody stools, unexplained weight loss, vomiting and other serious symptoms. You may have a more serious condition that OTC Nexium cannot treat.

    Your doctor may run some tests to determine if you have another illness or recommend taking prescription Nexium.

    I Am Trying To Stop Taking Nexium For Acid Reflux Been Using Apple Cider And Honey With Cinnamon Any Other Suggestions

    Nexium 24HR ClearMinis Acid Reducer &  Heartburn Relief Capsules

    Stopping Nexium is tough but totally worth it, when you consider the long-term effects of heartburn medications.

    Unfortunately, going off nexium can often make your stomach over-secrete acid as a rebound to being suppressed by the medication for a long time.

    You need to use a combination of setting your diet right and using natural remedies to finally transition out of Nexium.

    We will soon be publishing a guide to this, but meanwhile, here is a good resource from someone who has been through this process. We have reviewed it and find it largely in line with what the best doctors, who understand holistic medicine say about the subject.

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    Treating Heartburn And Gastro

    Heartburn is a feeling of burning pain in your lower chest, behind the breastbone. It comes from acid backing up from your stomach to your throat. You may have seen ads on American channels for heartburn drugs, such as pantoprazole , omeprazole , esomeprazole or lansoprazole . These drugs are called PPIs . They keep the stomach from making too much acid.

    In most cases, you dont need a PPI for heartburn. You can get relief from a less powerful drug. And when you do need a PPI, you should take the lowest dose for as short a time as possible. Heres why:

    Do you need a PPI?

    PPIs are powerful drugs. Studies suggest that more than half of the people who take PPIs probably do not need them. Simple heartburn can be relieved with antacids or other less powerful drugs.

    • Do you have heartburn every now and thenafter a big, spicy meal, for example? This kind of heartburn is uncomfortable, but it is not serious. You dont need a PPI. You can usually get relief from an antacid, like Rolaids or Tums, or an H2 blocker, such as Pepcid AC or Zantac.
    • Have you had heartburn more than twice a week for several weeks? Then you may have GERD . This is when acid made in the stomach backs up into your throat. Over time, it damages the lining of your esophagus . If your health care provider thinks you have GERD, you may need a PPI.

    PPIs have risks.

    If you need a PPI, taking a low dose for less than a year is probably safe. But taking a PPI for a year or longer has been linked to:

    Welcome To Prilosec 20 Mg Capsules

    Take this medication by mouth as directed by your doctor, usually once daily before a meal. This medication may also be given through a tube into the stomach . Dosage and length of treatment are based on your medical condition and response to treatment. In children, the dosage is also based on weight.

    Prilosec OTC is a 14-day regimen that can be used up to three times a year, but not more often than every 4 months. If you need to use Prilosec OTC for more than the three indicated 14-day courses of treatment, consult with your doctor.

    The active ingredient omeprazole works to fight heartburn differently from treatments like acid controllers/H2s or antacids. One of the best benefits of omeprazole is experiencing heartburn relief for 24 hours after only taking 1 pill a day.* But its not the only benefit. Omeprazole is a proton pump inhibitor and PPIs are the strongest class of frequent heartburn medicines.

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    What Are The Side Effects Of Esomeprazole

    With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.

    Contact your doctor immediately if you experience any of the following:

    • Allergic reactions: Rash, hives, difficulty breathing, swelling of face, lips, tongue, or throat
    • Severe stomach pain, diarrhea that is watery or bloody
    • Kidney problems: Blood in your urine, rapid weight gain, urinating more or less than usual
    • Low magnesium: Irregular heart rate, muscle cramps, tremors
    • New or worsening symptoms of lupus: Joint pain, skin rash on your arms or cheeks that gets worse in the sunlight

    The following side effects may get better over time as your body gets used to the medication. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time.

    How And When To Take It

    Nexium Control Treats Heartburn and Acid Reflux (Review)

    Always take esomeprazole exactly as your GP has told you. It’s usual to take it once a day in the morning.

    You can take it with or without food.

    If you take esomeprazole twice a day, take 1 dose in the morning and 1 dose in the evening.

    Swallow tablets whole with a drink of water.

    If you have problems swallowing tablets, you can put them in a glass of water. Stir until the tablet breaks up and drink straight away.

    If your child is under 12, their GP will prescribe granules which come in sachets. Mix granules with some water and drink straight away.

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    How Does Nexium Work

    The mucous membrane of the stomach consists of various highly specialized cells. Parietal cells are responsible for acid production and its delivery to the gastric juice. Using a specific transporter, acidic protons are released into the gastric juice in exchange with potassium ions . Nexium binds specifically to this transporter and irrevocably blocks it. This reduces the acidity of the gastric juice.

    Interesting: Structure of the gastric mucosaThe gastric mucosa consists of different, highly specialized cellsMain cells form enzymes , which are important for the breakdown and digestion of proteins that we ingest through foodSide cells form a slimy protective shield for the gastric mucosa, so that it is protected from the digestive enzymes and the acidic gastric juiceParietal cells release acidic protons into the gastric juice and are therefore responsible for the acidity of the gastric juice. They also produce the protein intrinsic factor, which is necessary for the absorption of vitamin B12 from food

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    Is Nexium Or Prilosec More Effective

    In trials comparing standard doses of Nexium 40 mg and Prilosec 20 mg in patients with GERD symptoms, Nexium provided the most acid control out of all of the drugs. In another study, patients treated with Nexium experienced faster symptom relief than patients treated with Prilosec and other PPIs. Although Nexium may be more effective, both drugs are quite popular among prescribers.

    The best medication is the one that works best for you, with the least amount of side effects. Consult your healthcare provider, who can help select the best drug for you based on your symptoms, medical condition, and other drugs you take that could interact with Nexium or Prilosec.

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